Sioux Falls is the regional medical hub of the Northern Plains: Avera Cancer Institute and Sanford Cancer Center offer advanced genomic sequencing, surgical oncology, and bone marrow transplants. Learn about top NCI institutions, leading hospital networks, clinical trials, and patient navigation in South Dakota.
While South Dakota does not have a freestanding NCI-designated facility within state borders, residents access premier care through the following accredited health systems and formal referral alliances:
ByOnco coordinates seamless virtual consultations and cross-state referrals with neighboring NCI Comprehensive Cancer Centers.
Active Phase I and precision oncology clinical trial programs at Avera and Sanford.
Avera Cancer Institute and Sanford Cancer Center in Sioux Falls are the leading cancer treatment centers in South Dakota and the Upper Midwest.
ByOnco connects patients across South Dakota to clinical specialists in Sioux Falls and top national cancer centers (such as Mayo Clinic Rochester), assisting with second opinions and 24/7 symptom tracking.
Connect with our clinical navigation team to verify center in-network status, organize second opinions, and review clinical trials.
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