Best Cancer Centers in the US
Across All 50 States

Home to the O'Neal Comprehensive Cancer Center at UAB, the only NCI-designated cancer center serving Alabama and the central Deep South.

Alaska patients frequently access specialized surgical oncology and Phase I trials through formalized direct referral pipelines to Fred Hutchinson Cancer Center in Seattle.

Arizona boasts world-class oncology powerhouses including Mayo Clinic in Phoenix/Scottsdale and University of Arizona Cancer Center in Tucson, with full access to proton therapy and targeted clinical trials.

The UAMS Myeloma Center in Little Rock is globally recognized as one of the premier destinations for multiple myeloma research, novel therapies, and autologous transplants.

California is the largest oncology innovation ecosystem in the United States, with 8 NCI-Designated Comprehensive Cancer Centers pioneering CAR-T therapy, precision genomics, and robotic surgery.

CU Cancer Center on the Anschutz Medical Campus is the premier Rocky Mountain destination for groundbreaking lung cancer genomics and targeted therapy trials.

Yale Cancer Center and Smilow Cancer Hospital are world leaders in checkpoint inhibitor discovery and immunotherapy research, backed by MSKCC care alliance pathways in Hartford.

The Helen F. Graham Cancer Center in Newark participates in the NCI Community Oncology Research Program (NCORP) with trial accrual rates that rival major academic centers.

Florida is a premier hub for both domestic and international oncology care, featuring Moffitt Cancer Center in Tampa, Sylvester in Miami, and Mayo Clinic in Jacksonville.

Georgia's oncology ecosystem in Atlanta includes Winship Cancer Institute of Emory University (Georgia's only NCI-Designated Comprehensive Cancer Center) and Northside Hospital, one of the highest-volume bone marrow transplant centers in America.

UH Cancer Center conducts critical research into the unique cancer genetics of Pacific Islander, Native Hawaiian, and Asian populations in partnership with Queen's Health.

St. Luke's Cancer Institute is Idaho's largest oncology provider, offering comprehensive radiation and medical oncology with direct referral pipelines to Huntsman Cancer Institute in Utah.

Chicago is a powerhouse of Midwestern oncology, anchored by Northwestern Lurie and University of Chicago, with world-class pediatric cancer care at Lurie Children's.

Indiana University Simon Comprehensive Cancer Center in Indianapolis is internationally famous as the birthplace of curative therapy for testicular cancer under Dr. Lawrence Einhorn.

Holden Comprehensive Cancer Center in Iowa City is Iowa's only NCI-designated center and a global destination for neuroendocrine tumor (NET) clinical trials and PRRT treatments.

The University of Kansas Cancer Center achieved Comprehensive designation in 2022, providing high-tier academic research and advanced cellular therapies across Kansas and Missouri.

UK Markey Cancer Center earned NCI Comprehensive designation in 2023, spearheading aggressive early screening and cutting-edge immunotherapies for Kentucky patients.

Louisiana boasts specialized regional oncology excellence through Ochsner Cancer Institute and Mary Bird Perkins, with deep expertise in surgical oncology and precision radiation.

Maine patients access top-tier clinical cancer care at Maine Medical Center in Portland, while Bar Harbor's Jackson Laboratory is one of the world's premier genetic cancer research hubs.

Maryland is a global epicenter of cancer medicine: Johns Hopkins Kimmel Cancer Center pioneered cancer genetic sequencing and modern checkpoint inhibitors, situated alongside the NIH Clinical Center in Bethesda.

Boston, Massachusetts is the undisputed biopharma and clinical oncology capital of the world. Dana-Farber / Harvard Cancer Center, Mass General, and Boston Children's lead the world in new drug discovery and pediatric cure rates.

Michigan features two elite NCI Comprehensive Cancer Centers: Rogel Cancer Center in Ann Arbor and Karmanos Cancer Institute in Detroit, supported by Corewell Health and Henry Ford.

Minnesota is home to Mayo Clinic in Rochester—consistently ranked the #1 hospital in the United States—as well as the Masonic Cancer Center, the birthplace of modern bone marrow transplantation.

UMMC Cancer Center in Jackson is the state's academic medical hub, partnering with regional networks to expand access to early cancer detection and targeted chemotherapy.

Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine in St. Louis treats more than 12,000 newly diagnosed cancer patients annually.

Billings Clinic Cancer Center is a member of the Mayo Clinic Care Network, offering Montana patients local expert oncology backed by Mayo Clinic specialist consultations.

The Fred & Pamela Buffett Cancer Center at Nebraska Medicine in Omaha is globally recognized for pioneering research in lymphoma and hematologic transplants.

Comprehensive Cancer Centers of Nevada in Las Vegas offers extensive Phase I-IV trials in affiliation with UCLA, providing frontline care while coordinating quaternary cases with Southern California NCI centers.

Dartmouth Cancer Center (formerly Norris Cotton) in Lebanon is one of only three NCI-designated comprehensive centers in northern New England, leading national models in rural oncology delivery.

Rutgers Cancer Institute of New Jersey in New Brunswick, in partnership with RWJBarnabas Health and the Jack & Sheryl Morris Cancer Center, is New Jersey's only NCI-Designated Comprehensive Cancer Center.

UNM Comprehensive Cancer Center in Albuquerque is the official cancer center of New Mexico, providing cutting-edge genomic sequencing and clinical trials for Hispanic and American Indian populations.

New York is a titan of global oncology, home to Memorial Sloan Kettering (the world's oldest and largest private cancer center), NYU Perlmutter, Columbia Herbert Irving, Mount Sinai Tisch, and Roswell Park in Buffalo.

North Carolina's Research Triangle is an elite oncology corridor, featuring Duke Cancer Institute, UNC Lineberger, and Wake Forest Baptist, alongside Charlotte's Levine Cancer Institute.

The Sanford Roger Maris Cancer Center in Fargo is the flagship oncology destination for the Dakotas and western Minnesota, delivering comprehensive radiation, chemotherapy, and clinical trials.

Ohio is a powerhouse of clinical oncology: Cleveland Clinic Taussig and Case Western lead in cancer surgery and imaging, The James in Columbus is one of America's largest freestanding cancer hospitals, and Cincinnati Children's is a global pediatric oncology leader.

Stephenson Cancer Center at OU Health is Oklahoma's only NCI-designated center, consistently ranking in the top tier nationwide for patient accrual to NCI National Clinical Trials Network studies.

OHSU Knight Cancer Institute in Portland, directed by Dr. Brian Druker (pioneer of Gleevec / imatinib), is internationally famed for pioneering targeted cancer therapy and early tumor detection technologies.

Pennsylvania is home to historic breakthroughs in cancer medicine: Penn's Abramson Cancer Center invented the world's first FDA-approved CAR-T cell therapy (Kymriah), and CHOP is globally revered for curing pediatric leukemias.

The Legorreta Cancer Center at Brown University and Lifespan Cancer Institute provide academic cancer therapies in Providence with direct linkages to Harvard/Dana-Farber networks in nearby Boston.

MUSC Hollings Cancer Center in Charleston is South Carolina's only NCI-Designated Comprehensive Cancer Center, offering statewide clinical trial access and mobile cancer screening units.

Sioux Falls is the regional medical hub of the Northern Plains: Avera Cancer Institute and Sanford Cancer Center offer advanced genomic sequencing, surgical oncology, and bone marrow transplants.

Tennessee holds legendary oncology standing: St. Jude Children's Research Hospital in Memphis (families never receive a bill for treatment) and Vanderbilt-Ingram Cancer Center in Nashville, the pioneer of targeted oncogenomics.

Texas is home to the world's largest medical complex, the Texas Medical Center in Houston, anchored by MD Anderson Cancer Center—consistently ranked the #1 cancer hospital in the world—and UT Southwestern in Dallas.

Huntsman Cancer Institute in Salt Lake City holds the world's largest genetic cancer database (the Utah Population Database), leading global discoveries in inherited cancer mutations (including BRCA1).

The University of Vermont Cancer Center in Burlington is an academic clinical center delivering high-tier surgical oncology, immunotherapy, and cancer clinical trials.

Virginia features two elite NCI Comprehensive Cancer Centers: VCU Massey in Richmond and UVA in Charlottesville, alongside Northern Virginia's Inova Schar Cancer Institute.

Fred Hutchinson Cancer Center in Seattle is a global beacon of hope: the birthplace of bone marrow transplantation under Nobel laureate Dr. E. Donnall Thomas and a pioneer of modern cellular immunotherapies.

Washington DC is anchored by Georgetown Lombardi Comprehensive Cancer Center and Children's National Hospital, providing world-class capital region oncology and pediatric cancer cure protocols.

WVU Cancer Institute in Morgantown is the flagship cancer program for West Virginia, offering advanced robotic surgery, precision radiation, and mobile mammography units.

UW Carbone Cancer Center in Madison was one of the nation's original six comprehensive cancer centers, recognized for pioneering tamoxifen and 5-FU fluorouracil chemotherapy.

Wyoming patients receive dedicated community oncology in Cheyenne and Casper, with formalized referral pathways to Huntsman Cancer Institute (Salt Lake City) and CU Cancer Center (Denver).