Midwest Region · St. Paul (Capital)

Best Cancer Centers in Minnesota (MN)

Minnesota is home to Mayo Clinic in Rochester—consistently ranked the #1 hospital in the United States—as well as the Masonic Cancer Center, the birthplace of modern bone marrow transplantation. Learn about top NCI institutions, leading hospital networks, clinical trials, and patient navigation in Minnesota.

NCI-Designated Cancer Centers in Minnesota

Mayo Clinic Comprehensive Cancer Center

Rochester, Minnesota

NCI-Designated Comprehensive Cancer Center
Key Specialties & Innovations:
Multidisciplinary Team CareProton Beam TherapySurgical InnovationCAR-T TherapyRare Cancers

Masonic Cancer Center, University of Minnesota

Minneapolis, Minnesota

NCI-Designated Comprehensive Cancer Center
Key Specialties & Innovations:
Umbilical Cord Blood & Bone Marrow TransplantImmunotherapyCancer Causes & Prevention

Additional Major Hospital Networks in Minnesota

  • M Health Fairview Cancer Care (Twin Cities)
  • Children's Minnesota Cancer and Blood Disorders
  • Park Nicollet Jane Brattain Breast Center

Clinical Trials & Precision Research in Minnesota

Global leader in cutting-edge clinical trials, rare cancer discovery, and advanced radiation therapy.

Need trial matching? ByOnco scans active National Cancer Institute (NCI) and ClinicalTrials.gov registers for your exact biomarker profile.

Frequently Asked Questions for Minnesota

Why is Mayo Clinic Rochester famous for cancer treatment?

Mayo Clinic in Rochester, MN brings together world-leading specialists across all oncologic disciplines for integrated, same-week diagnosis, genomic profiling, and customized treatment plans.

How does ByOnco help patients seeking care at Mayo Clinic?

ByOnco assists patients with medical appointment requests, insurance and self-pay cost estimation, and rapid record transfers for Mayo Clinic evaluations.